PROREACT « Seed Train »

PROREACT “SEED TRAIN”
3D-construction of a PROREACT seed train consisting of PROREACT P bioreactors of the sizes 10 L, 300 L, 1.000 L and 10.000 L with corresponding media and adjusting agents supply units. The plant is modularly installed within a steel construction with prefabricated subunits.

Defined conditions in series

Most large-scale bioprocesses are carried out in discontinuous batch and fed-batch processes. To start a production cycle, the cleaned and sterilized production bioreactor is filled with sterile medium and then inoculated with active biomass from a cascade of pre-culture fermenters (seed fermenters).

Both production and pre-culture fermenters meet the highest sterile standards and allow the cultivation of microorganisms under defined, controlled conditions.

FRINGS realizes the appropriate « seed trains » for production plants based on customer specifications or based on our own engineering and laboratory work

Seed trains are usually built within a « package unit » with central supply units and with a central control system.

The sizes of the individual stages, the equipment variants, the number and type of control medium templates and the layout planning can be selected in a variety of ways according to customer requirements. Usually, the basic data are determined in the course of pre-engineering in close cooperation with the end customer, the planning company and/or the general contractor.

CONTACT Biotech-Team

OBTENEZ DES CONSEILS MAINTENANT:

Tel.: +49 (0)22 26 89 29 – 400
biotech@frings.com

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HEINRICH FRINGS GMBH & CO. KG

Boschstraße 32 53359 Rheinbach
Tel.: +49 (0)22 26 89 29 – 400 Fax: +49 (0)22 26 89 29 – 401