Most large-scale bioprocesses are carried out in discontinuous batch and fed-batch processes. To start a production cycle, the cleaned and sterilized production bioreactor is filled with sterile medium and then inoculated with active biomass from a cascade of pre-culture fermenters (seed fermenters).
Both production and pre-culture fermenters meet the highest sterile standards and allow the cultivation of microorganisms under defined, controlled conditions.
FRINGS realizes the appropriate « seed trains » for production plants based on customer specifications or based on our own engineering and laboratory work
Seed trains are usually built within a « package unit » with central supply units and with a central control system.
The sizes of the individual stages, the equipment variants, the number and type of control medium templates and the layout planning can be selected in a variety of ways according to customer requirements. Usually, the basic data are determined in the course of pre-engineering in close cooperation with the end customer, the planning company and/or the general contractor.